Catney One: Frequently asked questions

Catney One is the phosphate power binder. Catney One is a feed supplement that improves renal function in cats with chronic kidney disease (CKD) by reducing phosphate absorption.

Lanthanum carbonate LA2 (CO3 )3 is the ingredient in Catney One. One stick of 520 mg Catney One granules contains at least 450 mg lanthanum carbonate octahydrate plus maltodextrins (from potatoes and corn). Lanthanum carbonate is a carbonate salt obtained from the rare earth element lanthanum. Lanthanum belongs to the group of so-called "lanthanoids", which are generally non-toxic and can hardly be absorbed by the intestine when administered with food (Cernaro et al, 2020). Lanthanum occurs naturally everywhere in the environment, including in salt and fresh water, but also in animal tissue. Lanthanoids have a high affinity for phosphorus and phosphates.

Starting from the stomach and via the digestive tract, lanthanum binds the phosphate from the cat's food and forms lanthanum phosphate, which is insoluble. Lanthanum carbonate is recommended by the IRIS (International Renal Interest Society) for phosphate reduction from IRIS stage II onwards. Since 2023, if the FGF-23 value is above the reference range of >400 pg/ml, IRIS also recommends the use of a phosphate binder from stage I onwards. 

One stick of Catney One per day is initially recommended to be be mixed with your cat's food. After 2–4 weeks, the amount can be adapted based on serum phosphate levels (blood monitoring).

Mix the granules well with the food. Administration can be distributed throughout the day to match the cat’s feeding habits. Always provide plenty of fresh drinking water.

Many cat caregivers are aware that certain products claiming phosphatebinding effects are meant to be given with each meal of the cat. Catney One has a high capacity to bind phosphate, much higher than comparable products. Therefore, only one application of Catney One per day with a meal is required. Although it is possible to divide the application over several meals.

One positive aspect of Catney One is, that it can be given with any type of food. No matter whether it is a conventional cat food or a special diet food. Catney One has a high capacity to bind phosphate, much higher than comparable products. Thus, Catney One achieves a sufficient reduction of phosphate from the feed mash even with conventional feed. Always provide plenty of fresh drinking water.

It is best to add Catney One to the cat’s main meal. Make sure the contents of the stick are mixed well with the cat’s food, so to not disturb the scent of the feed and the cat is ingesting Catney One well. For cats on a purely dry-food diet, we recommend mixing Catney One into a little wet food or cat paste, such as Add One. Combined with Add One or another cat paste, Catney One can also be given before the cat’s main meals. Always provide plenty of fresh drinking water.

Simultaneous use of both Catney One and Porus One is feasible without any concerns. 

Catney One can be given to the cat at any time of the day. However, ensure an interval of 1 hour after or 3 hours before giving other orally administered products and Catney One.  The simultaneous administration of Catney One and Porus One is feasible without any concerns.

Yes, Catney One is water-soluble.

Catney One remains effective for up to 24 hours.

Catney One is a feed supplement to support kidney function in chronic renal insufficiency & to reduce the absorption of phosphate. Lanthanum carbonate is recommended by the IRIS (International Renal Interest Society) for phosphate reduction from IRIS stage II. Since 2023, if the FGF-23 value is above the reference range of > 400 pg/ml, IRIS also recommends the use of a phosphate binder from stage I onwards. In the case of chronic kidney disease, the duration of use is initially 6 months. It is recommended to seek the advice of a veterinarian before feeding Catney One or when extending the feeding period. Catney One is suitable for cats of all ages and genders.

Even with a tenfold overdose of lanthanum carbonate, the ingredient in Catney One, no side effects were observed in cats. Lanthanum carbonate is absorbed in negligible amounts compared to other feed supplements for phosphate reduction, such as aluminum.

Other undesirable side effects include constipation, gastrointestinal complications and adynamic bone disease as well as hypercalcemia can be seen with other phosphate binders. 

No such adverse effects have been observed for lanthanum carbonate. Furthermore, unlike products containing calcium carbonate, Catney One has no negative effect on the electrolyte balance. 

How quickly and to what extent the effect occurs depends on the phosphate level of the individual cat, the food intake and the phosphate content of the food. Studies have shown that lanthanum carbonate significantly reduces the absorption and bioavailability of phosphorus in adult cats. We recommend regular blood tests after 2-4 weeks to determine whether the dose needs to be adjusted.

In the case of chronic kidney disease, the initial duration of use is 6 months. It is recommended to seek the advice of a vet before feeding Catney One or when extending the feeding period. Fresh water should always be available.

References

  • Cernaro, V., Calimeri, S., Laudani, A., & Santoro, D. (2020). Clinical Evaluation of the Safety, Efficacy and Tolerability of Lanthanum Carbonate in the Management of Hyperphosphatemia in Patients with End-Stage Renal Disease. Therapeutics and clinical risk management, 16, 871–880. https://doi.org/10.2147/TCRM.S196805

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